cdk2 polyclonal antibody (Proteintech)
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Proteintech
cdk2 polyclonal antibody
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Cdk2 Polyclonal Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 447 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cdk2 polyclonal antibody/product/Proteintech
Average 96 stars, based on 447 article reviews
Figure S2 . " width="250" height="auto" />Cdk2 Polyclonal Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 447 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cdk2 polyclonal antibody/product/Proteintech
Average 96 stars, based on 447 article reviews
cdk2 polyclonal antibody - by Bioz Stars,
2026-05
96/100 stars
Images
1) Product Images from "BET inhibitor in combination with BCG vaccine enhances antitumor efficacy and orchestrates T cell reprogramming for melanoma"
Article Title: BET inhibitor in combination with BCG vaccine enhances antitumor efficacy and orchestrates T cell reprogramming for melanoma
Journal: Cell Reports Medicine
doi: 10.1016/j.xcrm.2025.101995
Figure S2 . " title="... the expression of cell cycle-associated proteins (p-CDK1, PHH3, CDK2, and Cyclin A2) and DNA damage-associated protein γ-H2AX. ..." property="contentUrl" width="100%" height="100%"/>
Figure Legend Snippet: The involvement of T cells with the combined treatment of NHWD-870 and BCG in TME (A) Schematic diagram showing the main workflow of the single-cell process. (B) Uniform Manifold Approximation and Projection (UMAP) plot of T cells/NK cells. (C) Proportions of cell-cycle phase in CD4 + T cells and CD8 + T cells under different treatment conditions. (D) Monocle2 trajectory plot of CD4 + T cells; the color represents cell-cycle phase. (E) The expression of Mki67 and Top2a along the pseudotime of CD4 + T cells; cells from different treatment group were marked by different color. (F) Monocle2 trajectory plot of CD8 + T cells; the color represents cell-cycle phase. (G) The expression of Mki67 and Top2a along the pseudotime of CD8 + T cells; cells from different treatment group were marked by different color. (H and I) Activated primary T cells were treated with 3 or 6 nM NHWD-870 or BCG for 72 h. Western blot was conducted to analyze the expression of cell cycle-associated proteins (p-CDK1, PHH3, CDK2, and Cyclin A2) and DNA damage-associated protein γ-H2AX. GAPDH was used as the reference of loading quantity of protein sample. Data depict one representative experiment of three independent experiments. (J) Representative pictures of melanoma sections from different treatments using multiple immunohistochemistry with anti-CD3 (green), anti-Cyclin A2 (red), and anti-PPH3 (cyan). Yellow arrows indicate examples of Cyclin A2 + CD3 + or PHH3 + CD3 + cells. Scale bars, 40 μm. (K) Quantitative analysis of the proportion of Cyclin A2 + CD3 + or PHH3 + CD3 + cells in whole sections. (L) Histogram of the proportion of Ki67 + cells in CD4 + and CD8 + T cells in tumor tissues by flow cytometry. Data are shown as mean ± SEM. p values were calculated by unpaired two-sided t test. ∗ p < 0.05; ∗∗ p < 0.01; ∗∗∗ p < 0.001; ∗∗∗∗ p < 0.0001. See also
Techniques Used: Expressing, Western Blot, Immunohistochemistry, Flow Cytometry
Figure Legend Snippet:
Techniques Used: Recombinant, Control, Staining, Polymer, Multiplex Assay, Protease Inhibitor, Transfection, Gentle, Bicinchoninic Acid Protein Assay, Chromatin Immunoprecipitation, Magnetic Beads, Software